| 43752 |
Creator |
c3baa1aae2495d9fcf383c433b46bfe0 |
| 43752 |
Creator |
ext-80280a04465332208dd6a1a2e9e57b88 |
| 43752 |
Creator |
ext-39ac2b3581922ff7a85965089b96424d |
| 43752 |
Creator |
ext-4b4e64e2db3dc3bfd42335358d9594a0 |
| 43752 |
Creator |
ext-60d4032ffed79e479e761cb80d43924d |
| 43752 |
Creator |
ext-88791b48e1e818693fae33504bf3ee42 |
| 43752 |
Creator |
ext-b071e0760b817bb498e5e3089987b5d9 |
| 43752 |
Date |
2015-06-15 |
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Is Part Of |
repository |
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abstract |
We successfully demonstrate the synthesis of polymer microspheres using a single electrospray
source, and show their physical characterisation. Electrospray has proven to be a
versatile method to manufacture particles, giving tight control over size with quasi-monodisperse
size distributions. It is a liquid atomisation technique that generates a monodisperse
population of highly charged liquid droplets over a broad size range (nanometres to
tens of microns). The droplets contain liquid precursors for the in-flight synthesis
of particles, and control over the trajectory of these droplets can be precisely manipulated
with the use of electric fields to drive them to a grounded substrate. This study
reports a method to synthesize poly(lactic-co-glycolic) acid (PLGA) microspheres using
the electrospray and thermally induced phase separation (TIPS) techniques, followed
by subsequent freeze-drying, for particle production. These microspheres are of interest
as vehicles for controlled drug release systems |
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authorList |
authors |
| 43752 |
presentedAt |
ext-285046726863267f64eab0e0cdd834e2 |
| 43752 |
status |
nonPeerReviewed |
| 43752 |
type |
AcademicArticle |
| 43752 |
type |
Article |
| 43752 |
label |
Malik, S. A.; Ng, W. H.; Bowen, J. ; Tang, J.; Gomez, A.; Kenyon, A. J. and Day,
R. M. (2015). Electrospray synthesis of PLGA TIPS microspheres. In: Aerosol Technology
2015, 15-17 Jun 2015, Tampere, Finland. |
| 43752 |
label |
Malik, S. A.; Ng, W. H.; Bowen, J. ; Tang, J.; Gomez, A.; Kenyon, A. J. and Day, R.
M. (2015). Electrospray synthesis of PLGA TIPS microspheres. In: Aerosol Technology
2015, 15-17 Jun 2015, Tampere, Finland. |
| 43752 |
Title |
Electrospray synthesis of PLGA TIPS microspheres |
| 43752 |
in dataset |
oro |