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Creator |
c3baa1aae2495d9fcf383c433b46bfe0 |
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Creator |
ext-f0fbcf4f0b6e834a5c2de39273dbe660 |
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Creator |
ext-34a61ce36ffbd32b87e4bd4411909e8e |
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Creator |
ext-3b801a88baf01d3d6425849b52e578b2 |
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Creator |
ext-42dd56da9826fc77aa6e826f9a9517c0 |
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Creator |
ext-99a4158297a896e371add787f26c79a6 |
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Date |
2012-06-01 |
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Is Part Of |
repository |
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abstract |
Hydroxyapatite (HA) is a calcium phosphate bioceramic used commonly in tissue engineering
due to its excellent potential as a bone replacement material. Next generation implantation
technology will include functionalised HA surfaces to promote angiogenesis and osteogenesis
via implanted hormone and growth factor. However, functionalisation of difficult;
silicon substitution of monolith has long been considered a potential route to increasing
the number of active binding sites in HA. We demonstrate in this conference proceeding
(and accepted poster presentation) the surface modification/functionalisation of silicon
substituted HA (SiHA) with thiol groups following a reaction with MPTS (SH-SiHA);
an intimate bond is verified by a proof of principle attachment of a fluorescent probe. |
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authorList |
authors |
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presentedAt |
ext-51a7ece4fc8e3f5b5552192193021c5c |
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status |
nonPeerReviewed |
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type |
AcademicArticle |
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type |
Article |
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label |
Hadley, Martin J.; Jiang, Peih-Jeng; Mendes, Paula M.; Rowson, Neil A.; Bowen, James
and Grover, Liam M. (2012). Surface functionalisation of silicon-substituted apatite
xerogels. In: 9th World Biomaterials Congress, 1-5 Jun 2012, Chengdu, China. |
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label |
Hadley, Martin J.; Jiang, Peih-Jeng; Mendes, Paula M.; Rowson, Neil A.; Bowen,
James and Grover, Liam M. (2012). Surface functionalisation of silicon-substituted
apatite xerogels. In: 9th World Biomaterials Congress, 1-5 Jun 2012, Chengdu, China.
|
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Title |
Surface functionalisation of silicon-substituted apatite xerogels |
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in dataset |
oro |