| 43191 |
Creator |
c3baa1aae2495d9fcf383c433b46bfe0 |
| 43191 |
Creator |
ext-171343c9772d6843e86c5ce045d24fb7 |
| 43191 |
Creator |
ext-ead874787748cb5bc57cc10214052842 |
| 43191 |
Creator |
ext-512636d10b6206c9121e928611ecd536 |
| 43191 |
Creator |
ext-5b9bed661c40ac72a5ba110f27dbdcb8 |
| 43191 |
Creator |
ext-adb1db200eb168fd2969ce100ad20171 |
| 43191 |
Creator |
ext-ca1327242e6b9a2f8c54d5f47d76e75d |
| 43191 |
Date |
2010-10 |
| 43191 |
Is Part Of |
repository |
| 43191 |
Is Part Of |
p1748605X |
| 43191 |
abstract |
In this paper active screen plasma nitriding (ASPN) is used to chemically modify the
surface of UHMWPE. This is an unexplored and new area of research. ASPN allows the
homogeneous treatment of any shape or surface at low temperature; therefore, it was
thought that ASPN would be an effective technique to modify organic polymer surfaces.
ASPN experiments were carried out at 120 °C using a dc plasma nitriding unit with
a 25% N<sub>2</sub> and 75% H<sub>2</sub> atmosphere at 2.5 mbar of pressure. UHMWPE
samples treated for different time periods were characterized by nanoindentation,
FTIR, XPS, interferometry and SEM. A 3T3 fibroblast cell line was used for <i>in vitro</i>
cell culture experiments. Nanoindentation of UHMWPE showed that hardness and elastic
modulus increased with ASPN treatment compared to the untreated material. FTIR spectra
did not show significant differences between the untreated and treated samples; however,
some changes were observed at 30 min of treatment in the range of 1500–1700 cm<sup>−1</sup>
associated mainly with the presence of N−H groups. XPS studies showed that nitrogen
was present on the surface and its amount increased with treatment time. Interferometry
showed that no significant changes were observed on the surfaces after the treatment.
Finally, cell culture experiments and SEM showed that fibroblasts attached and proliferated
to a greater extent on the plasma-treated surfaces leading to the conclusion that
ASPN surface treatment can potentially significantly improve the biocompatibility
behaviour of polymeric materials. |
| 43191 |
authorList |
authors |
| 43191 |
issue |
5 |
| 43191 |
status |
peerReviewed |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335140 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335170 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335171 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335172 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335173 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335174 |
| 43191 |
uri |
http://data.open.ac.uk/oro/document/335335 |
| 43191 |
volume |
5 |
| 43191 |
type |
AcademicArticle |
| 43191 |
type |
Article |
| 43191 |
label |
Kaklamani, G.; Mehrban, N.; Chen, J.; Bowen, J. ; Dong, H.; Grover, L. and Stamboulis,
A. (2010). Effect of plasma surface modification on the biocompatibility of UHMWPE.
Biomedical Materials, 5(5), article no. 054102. |
| 43191 |
label |
Kaklamani, G.; Mehrban, N.; Chen, J.; Bowen, J. ; Dong, H.; Grover, L. and Stamboulis,
A. (2010). Effect of plasma surface modification on the biocompatibility of UHMWPE.
Biomedical Materials, 5(5), article no. 054102. |
| 43191 |
Title |
Effect of plasma surface modification on the biocompatibility of UHMWPE |
| 43191 |
in dataset |
oro |