Scaffolding (bioinformatics)

Scaffolding (bioinformatics)

Scaffolding is a technique used in bioinformatics. It is defined as follows: Link together a non-contiguous series of genomic sequences into a scaffold, consisting of sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences corresponding to read overlaps.

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enScaffolding is a technique used in bioinformatics. It is defined as follows: Link together a non-contiguous series of genomic sequences into a scaffold, consisting of sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences corresponding to read overlaps.
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PET contig scaffold.png
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enScaffolding is a technique used in bioinformatics. It is defined as follows: Link together a non-contiguous series of genomic sequences into a scaffold, consisting of sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences corresponding to read overlaps. When creating a draft genome, individual reads of DNA are second assembled into contigs, which, by the nature of their assembly, have gaps between them. The next step is to then bridge the gaps between these contigs to create a scaffold. This can be done using either optical mapping or mate-pair sequencing.
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Scaffolding (bioinformatics)
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enScaffolding (bioinformatics)
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Bioinformatics
Category:Bioinformatics
Category:Biological techniques and tools
Contig
File:PET contig scaffold.png
Haemophilus influenzae
Human Genome Project
Optical mapping
Reference genome
Sanger sequencing
SPAdes (software)
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eU1Z
m.0wx 3 s
Q16909432
Scaffolding (bioinformatics)
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Category:Bioinformatics
Category:Biological techniques and tools
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PET contig scaffold.png?width=300
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