Protein–protein interaction prediction
Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes.
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- enProtein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes.
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- enProtein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes. Experimentally, physical interactions between pairs of proteins can be inferred from a variety of techniques, including yeast two-hybrid systems, protein-fragment complementation assays (PCA), affinity purification/mass spectrometry, protein microarrays, fluorescence resonance energy transfer (FRET), and Microscale Thermophoresis (MST). Efforts to experimentally determine the interactome of numerous species are ongoing. Experimentally determined interactions usually provide the basis for computational methods to predict interactions, e.g. using homologous protein sequences across species. However, there are also methods that predict interactions de novo, without prior knowledge of existing interactions.
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- Protein–protein interaction prediction
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- enProtein–protein interaction prediction
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- img.jgi.doe.gov
- openwetware.org/wiki/Protein-protein_interaction_databases
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- Acetate CoA-transferase
- Bayesian method
- Bioinformatics
- BLAST
- Category:Proteomics
- Clustal
- Escherichia coli
- FastContact
- File:Alignment of the Rosette Stone protein Human Succinyl-CoA-Transferase with Acetate-CoA-Transferase subunits alpha and beta.png
- File:Phylogenetic Profiling Method.png
- File:Trp operon organization across three different bacterial species.png
- Gene prediction
- Homology (biology)
- Interactome
- Interolog
- Macromolecular docking
- Mass spectrometry
- Microscale Thermophoresis
- Phylogenetic profiling
- Protein Data Bank
- Protein–DNA interaction site predictor
- Protein-fragment complementation assay
- Protein function prediction
- Protein microarray
- Protein-protein docking
- Protein–protein interaction
- Protein structure prediction
- Protein structure prediction software
- SH2 domain
- SH3 domain
- Src family kinase
- Structural biology
- Tryptophan synthase
- Two-hybrid screening
- Van der Waals radius
- SameAs
- 4tofg
- m.0byj9x
- Q7251528
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- Category:Proteomics
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- Protein–protein interaction prediction?oldid=1094199628&ns=0
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- 25003
- Wikipage page ID
- 4350008
- Wikipage revision ID
- 1094199628
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