
Hepatitis C alternative reading frame stem-loop
Hepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome.
- Caption
- enPredicted secondary structure and sequence conservation of HCV_ARF_SL
- Comment
- enHepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome.
- Depiction
- Has abstract
- enHepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome. The core protein-coding region of the Hepatitis C virus (HCV) genome contains a +1 alternative reading frame(ARF) and two proposed phylogenetically conserved RNA helix-forming stem loop structures (IV and VII).The proteins translated from the ARF appear to be translated during the normal viral life cycle but are not essential to virus replication. The two predicted stem loops shown here (SLV and SLVI) are proposed to be important for HCV translation and repression; these stem loops are located downstream of the Internal ribosome entry site (IRES) but their functional role is unknown.
- Hypernym
- Motif
- Id
- enRF00620
- Is primary topic of
- Hepatitis C alternative reading frame stem-loop
- Label
- enHepatitis C alternative reading frame stem-loop
- Link from a Wikipage to another Wikipage
- Category:Cis-regulatory RNA elements
- Category:Hepatitis C virus
- Cis-regulatory element
- Hepatitis C stem-loop IV
- Hepatitis C virus
- Hepatitis C virus stem-loop VII
- Hepatitis E virus cis-reactive element
- Internal ribosome entry site
- Reading frame
- RNA
- Secondary structure
- Sequence conservation
- Stem loop
- Translation (biology)
- Virus
- Name
- enHepatitis C alternative reading frame stem-loop
- Rfam
- enRF00620
- RnaType
- Cis-regulatory element
- SameAs
- 4mRZ4
- Hepatitis C alternative reading frame stem-loop
- m.03ccb5s
- Q5731709
- Subject
- Category:Cis-regulatory RNA elements
- Category:Hepatitis C virus
- Symbol
- enHCV_ARF_SL
- TaxDomain
- enViruses
- Thumbnail
- WasDerivedFrom
- Hepatitis C alternative reading frame stem-loop?oldid=1041726539&ns=0
- WikiPageLength
- 2238
- Wikipage page ID
- 13629231
- Wikipage revision ID
- 1041726539
- WikiPageUsesTemplate
- Template:Infobox rfam
- Template:Molecular-cell-biology-stub
- Template:Reflist
- Template:Rfam
- Template:SO