Hepatitis C alternative reading frame stem-loop

Hepatitis C alternative reading frame stem-loop

Hepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome.

Caption
enPredicted secondary structure and sequence conservation of HCV_ARF_SL
Comment
enHepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome.
Depiction
RF00620.jpg
Has abstract
enHepatitis C alternative reading frame stem-loop is a conserved secondary structure motif identified in the RNA genome of the Hepatitis C virus (HCV) which is proposed to have an important role in regulating translation and repression of the viral genome. The core protein-coding region of the Hepatitis C virus (HCV) genome contains a +1 alternative reading frame(ARF) and two proposed phylogenetically conserved RNA helix-forming stem loop structures (IV and VII).The proteins translated from the ARF appear to be translated during the normal viral life cycle but are not essential to virus replication. The two predicted stem loops shown here (SLV and SLVI) are proposed to be important for HCV translation and repression; these stem loops are located downstream of the Internal ribosome entry site (IRES) but their functional role is unknown.
Hypernym
Motif
Id
enRF00620
Is primary topic of
Hepatitis C alternative reading frame stem-loop
Label
enHepatitis C alternative reading frame stem-loop
Link from a Wikipage to another Wikipage
Category:Cis-regulatory RNA elements
Category:Hepatitis C virus
Cis-regulatory element
Hepatitis C stem-loop IV
Hepatitis C virus
Hepatitis C virus stem-loop VII
Hepatitis E virus cis-reactive element
Internal ribosome entry site
Reading frame
RNA
Secondary structure
Sequence conservation
Stem loop
Translation (biology)
Virus
Name
enHepatitis C alternative reading frame stem-loop
Rfam
enRF00620
RnaType
Cis-regulatory element
SameAs
4mRZ4
Hepatitis C alternative reading frame stem-loop
m.03ccb5s
Q5731709
Subject
Category:Cis-regulatory RNA elements
Category:Hepatitis C virus
Symbol
enHCV_ARF_SL
TaxDomain
enViruses
Thumbnail
RF00620.jpg?width=300
WasDerivedFrom
Hepatitis C alternative reading frame stem-loop?oldid=1041726539&ns=0
WikiPageLength
2238
Wikipage page ID
13629231
Wikipage revision ID
1041726539
WikiPageUsesTemplate
Template:Infobox rfam
Template:Molecular-cell-biology-stub
Template:Reflist
Template:Rfam
Template:SO