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53302 Creator 0e2d1b90682e8c08761586c8975c7f13
53302 Creator 538c0722d7d106c7098d06ea38e69498
53302 Creator cf4025dee845929a398330b0f5873116
53302 Creator ext-bf87095e26fd27b19799d161fbda6f89
53302 Creator ext-4c7784501bf12a7981295bc46736431f
53302 Date 2018-02
53302 Date 2018-02
53302 Is Part Of repository
53302 Is Part Of p02776715
53302 abstract We describe some simple techniques for investigating 2 key assumptions of the self-controlled case series (SCCS) method, namely, that events do not influence subsequent exposures and that events do not influence the length of observation periods. For each assumption, we propose some simple tests based on the standard SCCS model, along with associated graphical displays. The methods also enable the user to investigate the robustness of the results obtained using the standard SCCS model to failure of assumptions. The proposed methods are investigated by simulations and applied to data on measles, mumps and rubella vaccine, and antipsychotics.
53302 abstract We describe some simple techniques for investigating 2 key assumptions of the self-controlled case series (SCCS) method, namely, that events do not influence subsequent exposures and that events do not influence the length of observation periods. For each assumption, we propose some simple tests based on the standard SCCS model, along with associated graphical displays. The methods also enable the user to investigate the robustness of the results obtained using the standard SCCS model to failure of assumptions. The proposed methods are investigated by simulations and applied to data on measles, mumps and rubella vaccine, and antipsychotics.
53302 authorList authors
53302 issue 4
53302 issue 4
53302 status published
53302 status peerReviewed
53302 volume 37
53302 volume 37
53302 type AcademicArticle
53302 type Article
53302 label Whitaker, Heather J. ; Ghebremichael-Weldeselassie, Yonas ; Douglas, Ian J.; Smeeth, Liam and Farrington, C. Paddy (2018). Investigating the assumptions of the self-controlled case series method. Statistics in Medicine, 37(4) pp. 643–658.
53302 label Whitaker, Heather J. ; Ghebremichael-Weldeselassie, Yonas ; Douglas, Ian J.; Smeeth, Liam and Farrington, C. Paddy (2018). Investigating the assumptions of the self-controlled case series method. Statistics in Medicine, 37(4) pp. 643–658.
53302 Publisher ext-dfec3621c63b727aea32091d7bde7514
53302 Title Investigating the assumptions of the self-controlled case series method
53302 Title Investigating the assumptions of the self-controlled case series method
53302 in dataset oro