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Creator |
a5841b98ed42418276d2e88035d61953 |
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Creator |
25f5503348bcfe7d5ff29d613946ff35 |
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Date |
2014 |
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Is Part Of |
repository |
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Is Part Of |
pb01ae46b7c1353d89e2799e877c83414 |
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abstract |
Breath analysis is a promising field with great potential for non-invasive diagnosis
of a number of disease states. Analysis of the concentrations of volatile organic
compounds (VOCs) in breath with an acceptable accuracy are assessed by means of using
analytical techniques with high sensitivity, accuracy, precision, low response time,
and low detection limit, which are desirable characteristics for the detection of
VOCs in human breath. “Breath fingerprinting”, indicative of a specific clinical status,
relies on the use of multivariate statistics methods with powerful in-built algorithms.
The need for standardisation of sample collection and analysis is the main issue concerning
breath analysis, blocking the introduction of breath tests into clinical practice.
This review describes recent scientific developments in basic research and clinical
applications, namely issues concerning sampling and biochemistry, highlighting the
diagnostic potential of breath analysis for disease diagnosis. Several considerations
that need to be taken into account in breath analysis are documented here, including
the growing need for metabolomics to deal with breath profiles. |
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authorList |
authors |
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issue |
2 |
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status |
peerReviewed |
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uri |
http://data.open.ac.uk/oro/document/246348 |
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uri |
http://data.open.ac.uk/oro/document/246349 |
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uri |
http://data.open.ac.uk/oro/document/246350 |
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uri |
http://data.open.ac.uk/oro/document/246351 |
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uri |
http://data.open.ac.uk/oro/document/246352 |
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uri |
http://data.open.ac.uk/oro/document/246353 |
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uri |
http://data.open.ac.uk/oro/document/246354 |
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uri |
http://data.open.ac.uk/oro/document/246593 |
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volume |
4 |
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type |
AcademicArticle |
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type |
Article |
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label |
Lourenco, Celia and Turner, Claire (2014). Breath analysis in disease diagnosis:
methodological considerations and applications. Metabolites, 4(2) pp. 465–498.
|
| 40513 |
label |
Lourenco, Celia and Turner, Claire (2014). Breath analysis in disease diagnosis:
methodological considerations and applications. Metabolites, 4(2) pp. 465–498. |
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Title |
Breath analysis in disease diagnosis: methodological considerations and applications |
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in dataset |
oro |