Chem-seq

Chem-seq

Chem-seq is a technique that is used to map genome-wide interactions between small molecules and their protein targets in the chromatin of eukaryotic cell nuclei. The method employs chemical affinity capture coupled with massively parallel DNA sequencing to identify genomic sites where small molecules interact with their target proteins or DNA. It was first described by Lars Anders et al. in the January, 2014 issue of "Nature Biotechnology".

Comment
enChem-seq is a technique that is used to map genome-wide interactions between small molecules and their protein targets in the chromatin of eukaryotic cell nuclei. The method employs chemical affinity capture coupled with massively parallel DNA sequencing to identify genomic sites where small molecules interact with their target proteins or DNA. It was first described by Lars Anders et al. in the January, 2014 issue of "Nature Biotechnology".
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Chem-seq Workflow.png
Has abstract
enChem-seq is a technique that is used to map genome-wide interactions between small molecules and their protein targets in the chromatin of eukaryotic cell nuclei. The method employs chemical affinity capture coupled with massively parallel DNA sequencing to identify genomic sites where small molecules interact with their target proteins or DNA. It was first described by Lars Anders et al. in the January, 2014 issue of "Nature Biotechnology".
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Technique
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Chem-seq
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enChem-seq
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Affinity capture
AT7519
Biotinylation
BRD2
BRD3
BRD4
Bromodomain
Category:Biotechnology
Category:DNA
Category:Molecular biology techniques
Category:Protein methods
CDK9
Cell nuclei
ChIP-seq
Chromatin
Dimethyl sulfoxide
DNA binding protein
DNA sequencing
Eukaryotic
File:Chem-seq Workflow.png
Genome
Intercalation (biochemistry)
In vitro
In vivo
JQ1
Ligands
Molecules
Multiple myeloma
Nature Biotechnology
Protein
Psoralen
Sonicated
Streptavidin
Therapeutic modalities
Transcription factor
SameAs
Chem-seq
fdRn
m.0 v51s2
Q17084707
رسم مخطط مقياس الجينيوم
Subject
Category:Biotechnology
Category:DNA
Category:Molecular biology techniques
Category:Protein methods
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Wikipage revision ID
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